Green Coffee Bean Extract
Green coffee bean extract (GCBE) comes from coffee beans that have not yet been roasted. Coffee beans that haven’t been roasted have much higher levels of chlorogenic acids, which are thought to have health benefits that include weight loss and blood pressure reduction.
Early research suggests that taking green coffee extracts containing 50 mg to 140 mg of chlorogenic acids daily for between 4 to 12 weeks can reduce blood pressure (reference 2). GCBE may also reduce body weight in overweight individuals through the prevention of carbohydrate uptake from the intestines after a meal (reference 1). An increase in vascular responsiveness has been noted as well, due in part to the metabolite ferulic acid.
GCBE contains caffeine, similar to traditional coffee. Therefore, green coffee can cause caffeine-related side effects similar to coffee. Caffeine can cause insomnia, nervousness and restlessness, stomach upset, nausea and vomiting, increased heart and breathing rate, and other side effects. Consuming large amounts of GCBE might also cause headache, anxiety, agitation, ringing in the ears, and irregular heartbeats.
No synergies of note.
Studies using GCBE have concluded that the recommended intake is between 240-600mg for a 50% chlorogenic acid supplement.
1. Vinson JA1, Burnham BR, Nagendran MV Randomized, double-blind, placebo-controlled, linear dose, crossover study to evaluate the efficacy and safety of a green coffee bean extract in overweight subjects. Diabetes Metab Syndr Obes. (2012)
2. Watanabe T, et al The blood pressure-lowering effect and safety of chlorogenic acid from green coffee bean extract in essential hypertension . Clin Exp Hypertens. (2006)